Feb 6, 2025

INDIA EDITION

Guillain-Barré Syndrome: A Rare Disorder Spreading Rapidly in India

Guillain-Barré Syndrome: A Rare Disorder Spreading Rapidly in India

Pune and its surrounding regions are currently witnessing an alarming spike in Guillain-Barré Syndrome (GBS), a rare neurological disorder that causes sudden numbness, muscle weakness, and even paralysis. Health officials have reported 163 cases in Maharashtra alone and 5 suspected deaths so far.

Pune and its surrounding regions are currently witnessing an alarming spike in Guillain-Barré Syndrome (GBS), a rare neurological disorder that causes sudden numbness, muscle weakness, and even paralysis. Health officials have reported 163 cases in Maharashtra alone and 5 suspected deaths so far.

health

health

Written By

Written By

Sanvi Agarwal

Sanvi Agarwal

Published

Published

Feb 3, 2025

Feb 3, 2025

Understanding Guillain-Barré Syndrome

GBS is an autoimmune disorder in which the body's immune system mistakenly attacks the nerves. It often begins with weakness and tingling sensations in the feet and legs, which then spread to the upper body. In severe cases, it can lead to complete paralysis, including respiratory muscles, requiring ventilator support.

While the exact cause of GBS remains unknown, it is often triggered by infections, including bacterial or viral illnesses. Campylobacter jejuni, a bacteria commonly found in contaminated food and water, has been identified as a potential cause of the outbreak in Pune. Other known triggers include recent vaccinations, surgeries, and underlying neuropathy.

The outbreak in Pune and surrounding districts has been attributed to possible water contamination. The Rapid Response Teams (RRTs) in Pune are actively investigating the situation, conducting household surveys, collecting water samples, and interviewing residents. 

Deputy Chief Minister Ajit Pawar, who is also the Pune district guardian minister, has instructed health officials to ensure an adequate supply of drugs for GBS treatment. Additionally, he has directed authorities to take strict action against hospitals that overcharge GBS patients.

Apart from Maharashtra, isolated cases of GBS have also been reported in other states. Telangana recently confirmed its first GBS case, a 25-year-old woman from Siddipet. Meanwhile, Kolkata has also recorded multiple pediatric cases, with several children receiving treatment in hospitals across the city.

Why is a Rare Disease Becoming So Prevalent?

GBS is considered a rare disorder, with an estimated incidence of 1-2 cases per 100,000 people worldwide. However, the sudden spike in cases in Pune suggests environmental or infectious triggers. Health experts believe that the presence of Campylobacter jejuni in contaminated water sources is a significant contributing factor. To contain the spread, Pune’s health authorities are actively monitoring water sources, urging residents to consume only purified water and maintain proper hygiene. Meanwhile, hospitals have been instructed to report all suspected cases to health departments to ensure prompt medical intervention.

Symptoms and Complications of GBS

The symptoms of GBS typically begin with mild tingling and weakness in the lower limbs, which gradually progress upwards. Other symptoms include:

  • Unsteady walking

  • Difficulty in climbing stairs

  • Severe cramping

  • Double vision

  • Rapid heart rate

  • Low blood pressure

  • A "pins and needles" sensation in fingers, toes, ankles, and wrists

If left untreated, GBS can lead to severe complications such as:

  • Paralysis of respiratory muscles, requiring ventilator support

  • Heart-related issues

  • Pain and muscle atrophy

  • Impaired bowel and bladder function

  • Blood clots due to immobility

While GBS is not contagious, its post-infectious nature means that it can develop after a viral or bacterial illness. Some patients may experience relapses even after recovery.

Early detection of Guillain-Barré Syndrome is critical in preventing severe complications. Since the disease progresses rapidly, those experiencing symptoms such as numbness, muscle weakness, or difficulty walking should seek medical attention immediately. Timely diagnosis allows for prompt medical intervention, which can prevent paralysis and improve the chances of full recovery. If you or someone you know is experiencing any of these symptoms, do not ignore them—getting checked could be life-saving.

The Necessities We Are Failing to Provide

Water, food, and shelter—these are the three fundamental necessities for human survival. Yet, time and again, we fail to ensure the most basic of these. Water contamination is a recurring problem in many parts of India, leading not only to outbreaks like GBS but also to numerous other waterborne diseases. The current crisis highlights the urgent need for better water management and sanitation policies. It is unacceptable that people continue to suffer due to lack of clean water in a time when technology and resources to prevent such crises exist. The government and local authorities must take proactive steps to prevent future outbreaks by strengthening disease surveillance systems, improving water quality monitoring, and raising awareness about the disease.


Understanding Guillain-Barré Syndrome

GBS is an autoimmune disorder in which the body's immune system mistakenly attacks the nerves. It often begins with weakness and tingling sensations in the feet and legs, which then spread to the upper body. In severe cases, it can lead to complete paralysis, including respiratory muscles, requiring ventilator support.

While the exact cause of GBS remains unknown, it is often triggered by infections, including bacterial or viral illnesses. Campylobacter jejuni, a bacteria commonly found in contaminated food and water, has been identified as a potential cause of the outbreak in Pune. Other known triggers include recent vaccinations, surgeries, and underlying neuropathy.

The outbreak in Pune and surrounding districts has been attributed to possible water contamination. The Rapid Response Teams (RRTs) in Pune are actively investigating the situation, conducting household surveys, collecting water samples, and interviewing residents. 

Deputy Chief Minister Ajit Pawar, who is also the Pune district guardian minister, has instructed health officials to ensure an adequate supply of drugs for GBS treatment. Additionally, he has directed authorities to take strict action against hospitals that overcharge GBS patients.

Apart from Maharashtra, isolated cases of GBS have also been reported in other states. Telangana recently confirmed its first GBS case, a 25-year-old woman from Siddipet. Meanwhile, Kolkata has also recorded multiple pediatric cases, with several children receiving treatment in hospitals across the city.

Why is a Rare Disease Becoming So Prevalent?

GBS is considered a rare disorder, with an estimated incidence of 1-2 cases per 100,000 people worldwide. However, the sudden spike in cases in Pune suggests environmental or infectious triggers. Health experts believe that the presence of Campylobacter jejuni in contaminated water sources is a significant contributing factor. To contain the spread, Pune’s health authorities are actively monitoring water sources, urging residents to consume only purified water and maintain proper hygiene. Meanwhile, hospitals have been instructed to report all suspected cases to health departments to ensure prompt medical intervention.

Symptoms and Complications of GBS

The symptoms of GBS typically begin with mild tingling and weakness in the lower limbs, which gradually progress upwards. Other symptoms include:

  • Unsteady walking

  • Difficulty in climbing stairs

  • Severe cramping

  • Double vision

  • Rapid heart rate

  • Low blood pressure

  • A "pins and needles" sensation in fingers, toes, ankles, and wrists

If left untreated, GBS can lead to severe complications such as:

  • Paralysis of respiratory muscles, requiring ventilator support

  • Heart-related issues

  • Pain and muscle atrophy

  • Impaired bowel and bladder function

  • Blood clots due to immobility

While GBS is not contagious, its post-infectious nature means that it can develop after a viral or bacterial illness. Some patients may experience relapses even after recovery.

Early detection of Guillain-Barré Syndrome is critical in preventing severe complications. Since the disease progresses rapidly, those experiencing symptoms such as numbness, muscle weakness, or difficulty walking should seek medical attention immediately. Timely diagnosis allows for prompt medical intervention, which can prevent paralysis and improve the chances of full recovery. If you or someone you know is experiencing any of these symptoms, do not ignore them—getting checked could be life-saving.

The Necessities We Are Failing to Provide

Water, food, and shelter—these are the three fundamental necessities for human survival. Yet, time and again, we fail to ensure the most basic of these. Water contamination is a recurring problem in many parts of India, leading not only to outbreaks like GBS but also to numerous other waterborne diseases. The current crisis highlights the urgent need for better water management and sanitation policies. It is unacceptable that people continue to suffer due to lack of clean water in a time when technology and resources to prevent such crises exist. The government and local authorities must take proactive steps to prevent future outbreaks by strengthening disease surveillance systems, improving water quality monitoring, and raising awareness about the disease.


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Thursday, February 6, 2025